p53: From Fundamental Biology to Clinical Applications in Cancer

p53: From Fundamental Biology to Clinical Applications in Cancer

p53 tumour suppressor gene is our major barrier against neoplastic transformation. It is involved in many cellular functions, including cell cycle arrest, senescence, DNA repair, apoptosis, autophagy, cell metabolism, ferroptosis, immune system regulation, generation of reactive oxygen species, mito...

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Bibliographic Details
Main Authors: Maurizio Capuozzo, Mariachiara Santorsola, Marco Bocchetti, Francesco Perri, Marco Cascella, Vincenza Granata, Venere Celotto, Oreste Gualillo, Alessia Maria Cossu, Guglielmo Nasti, Michele Caraglia, Alessandro Ottaiano
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biology
Subjects:
p53
tp53
cancer
DNA repair
tumour progression
Online Access:https://www.mdpi.com/2079-7737/11/9/1325

Internet

https://www.mdpi.com/2079-7737/11/9/1325

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