Gene and metabolite expression dependence on body mass index in human myocardium

Gene and metabolite expression dependence on body mass index in human myocardium

Abstract We hypothesized that body mass index (BMI) dependent changes in myocardial gene expression and energy-related metabolites underlie the biphasic association between BMI and mortality (the obesity paradox) in cardiac surgery. We performed transcriptome profiling and measured a panel of 144 me...

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Bibliographic Details
Main Authors: Adewale S. Adebayo, Marius Roman, Mustafa Zakkar, Syabira Yusoff, Melanie Gulston, Lathishia Joel-David, Bony Anthony, Florence Y. Lai, Antonio Murgia, Bryony Eagle-Hemming, Sophia Sheikh, Tracy Kumar, Hardeep Aujla, Will Dott, Julian L. Griffin, Gavin J. Murphy, Marcin J. Woźniak
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-05562-8

Internet

https://doi.org/10.1038/s41598-022-05562-8

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