Probing novel epitopes on the Plasmodium falciparum circumsporozoite protein for vaccine development

Probing novel epitopes on the Plasmodium falciparum circumsporozoite protein for vaccine development

Abstract RTS,S and R21 are the only vaccines recommended by the WHO to protect children from Plasmodium falciparum (Pf) clinical malaria. Both vaccines target the Pf sporozoite surface protein circumsporozoite protein (CSP). Recent studies showed that human antibodies neutralize Pf sporozoites most...

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Bibliographic Details
Main Authors: Pascal S. Krenger, Magali Roques, Anne-Cathrine S. Vogt, Alessandro Pardini, Dominik A. Rothen, Ina Balke, Sophie T. Schnider, Mona O. Mohsen, Volker T. Heussler, Andris Zeltins, Martin F. Bachmann
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-024-01006-8

Internet

https://doi.org/10.1038/s41541-024-01006-8

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