Ultrasensitive single-step CRISPR detection of monkeypox virus in minutes with a vest-pocket diagnostic device

Abstract The emerging monkeypox virus (MPXV) has raised global health concern, thereby highlighting the need for rapid, sensitive, and easy-to-use diagnostics. Here, we develop a single-step CRISPR-based diagnostic platform, termed SCOPE (Streamlined CRISPR On Pod Evaluation platform), for field-dep...

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Bibliographic Details
Main Authors: Yunxiang Wang, Hong Chen, Kai Lin, Yongjun Han, Zhixia Gu, Hongjuan Wei, Kai Mu, Dongfeng Wang, Liyan Liu, Ronghua Jin, Rui Song, Zhen Rong, Shengqi Wang
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-47518-8