Parasitemia and antibody response to benznidazole treatment in a cohort of patients with chronic Chagas disease

Parasitemia and antibody response to benznidazole treatment in a cohort of patients with chronic Chagas disease

BackgroundEvaluating the effectiveness of Chagas disease treatment poses challenges due to the lack of biomarkers for disease progression and therapeutic response. In this study, we aimed to assess the clearance of Trypanosoma cruzi (T. cruzi) parasites in a group of benznidazole (BNZ)-treated chron...

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Main Authors: Carlos Henrique Valente Moreira, Ana Luiza Bierrenbach, Cesar Augusto Taconeli, Léa Campos de Oliveira-da Silva, Lewis F. Buss, Sheila M. Keating, Erika Regina Manuli, Noemia Barbosa Carvalho, Cristina Guastini, Sonia Bakkour Coco, José Ângelo Lauletta Lindoso, Lucas Augusto Moyses Franco, Fabio Ghilardi, Flavia Cristina da Silva Sales, Paul Contestable, Clara Di Germanio, Michael P. Busch, Ester Cerdeira Sabino
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Parasitology
Subjects:
Chagas
Trypanossoma cruzi
benznidazole
serology
PCR
biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fpara.2023.1235925/full

Internet

https://www.frontiersin.org/articles/10.3389/fpara.2023.1235925/full

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