Design, synthesis and in vitro biological activities of coumarin linked 1,3,4-oxadiazole hybrids as potential multi-target directed anti-Alzheimer agents

Design, synthesis and in vitro biological activities of coumarin linked 1,3,4-oxadiazole hybrids as potential multi-target directed anti-Alzheimer agents

Introduction: Alzheimer’s disease (AD) is one of the most common and prevalent forms of neurodegenerative diseases. Coumarin is a versatile scaffold that exhibits a wide range of biological properties including cholinesterase inhibitory activity and therefore is an important heterocyclic moiety to d...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Namy George, Bushra Al Sabahi, Majed AbuKhader, Khalid Al Balushi, Md. Jawaid Akhtar, Shah Alam Khan
Format: Artykuł
Język:English
Wydane: Elsevier 2022-06-01
Seria:Journal of King Saud University: Science
Hasła przedmiotowe:
Acetylcholinesterase
Alzheimer’s disease
Butyrylcholinesterase
Hybridization
Multi-target directed ligands
Dostęp online:http://www.sciencedirect.com/science/article/pii/S1018364722001586

Internet

http://www.sciencedirect.com/science/article/pii/S1018364722001586

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