Down-regulation of habenular calcium-dependent secretion activator 2 induces despair-like behavior

Down-regulation of habenular calcium-dependent secretion activator 2 induces despair-like behavior

Abstract Calcium-dependent secretion activator 2 (CAPS2) regulates the trafficking and exocytosis of neuropeptide-containing dense-core vesicles (DCVs). CAPS2 is prominently expressed in the medial habenula (MHb), which is related to depressive behavior; however, how MHb neurons cause depressive sym...

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Bibliographic Details
Main Authors: Hyeijung Yoo, Soo Hyun Yang, Jin Yong Kim, Esther Yang, Hyung Sun Park, Se Jeong Lee, Im Joo Rhyu, Gustavo Turecki, Hyun Woo Lee, Hyun Kim
Format: Article
Language:English
Published: Nature Portfolio 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-83310-0

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https://doi.org/10.1038/s41598-021-83310-0

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