Cerebral endothelial cell-derived extracellular vesicles regulate microglial polarization and promote autophagy via delivery of miR-672-5p

Abstract The interaction between cerebral endothelial cells (CEC) and brain parenchymal cells is critical to maintain neurovascular homeostasis, whereas extracellular vesicles (EVs) are essential to mediate the cell–cell communication. Previous researches demonstrated that CEC-derived EVs (CEC-EVs)...

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Bibliographic Details
Main Authors: Changshui Wang, Lei Feng, Li Zhu, Linlin Wu, Beibei Chen, Changmeng Cui, Mengqi Yang, Yahao Gao, Pei Jiang
Format: Article
Language:English
Published: Nature Publishing Group 2023-09-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06173-5