Comparison of the effects of fentanyls and other μ opioid receptor agonists on the electrical activity of respiratory muscles in the rat

Comparison of the effects of fentanyls and other μ opioid receptor agonists on the electrical activity of respiratory muscles in the rat

Introduction: Deaths due to overdose of fentanyls result primarily from depression of respiration. These potent opioids can also produce muscle rigidity in the diaphragm and the chest muscles, a phenomenon known as Wooden Chest Syndrome, which further limits ventilation.Methods: We have compared the...

Full description

Bibliographic Details
Main Authors: Damiana Cavallo, Eamonn Kelly, Graeme Henderson, Ana Paula Abdala Sheikh
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Pharmacology
Subjects:
wooden chest syndrome (WCS)
fentanyl
opioids
respiratory depression
muscle rigidity
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1277248/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1277248/full

Similar Items