Live Cell Imaging Reveals HBV Capsid Translocation from the Nucleus To the Cytoplasm Enabled by Cell Division

ABSTRACT Hepatitis B virus (HBV) capsid assembly is traditionally thought to occur predominantly in the cytoplasm, where the virus gains access to the virion egress pathway. To better define sites of HBV capsid assembly, we carried out single cell imaging of HBV Core protein (Cp) subcellular traffic...

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Bibliographic Details
Main Authors: Sofia Romero, Nuruddin Unchwaniwala, Edward L. Evans, Kevin W. Eliceiri, Daniel D. Loeb, Nathan M. Sherer
Format: Article
Language:English
Published: American Society for Microbiology 2023-04-01
Series:mBio
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Online Access:https://journals.asm.org/doi/10.1128/mbio.03303-22