Polymyxin B-Induced Kidney Injury Assessment of a Novel Formulation of Polymyxin B (VRP-034) in Rats

Despite the crucial role of Polymyxin-B in treating life-threatening gram-negative infections, its clinical utility is limited due to the risk of acute kidney injury. In response, a novel formulation of polymyxin-B is being developed to mitigate drug-induced kidney injury. In this study, we have ass...

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Bibliographic Details
Main Authors: Dilip Roy, Amol Kulkarni, Manu Chaudhary, Saransh Chaudhary, Anurag Payasi, Anmol Aggarwal
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Antibiotics
Subjects:
Online Access:https://www.mdpi.com/2079-6382/10/4/359