Myo5b Transports Fibronectin-Containing Vesicles and Facilitates FN1 Secretion from Human Pleural Mesothelial Cells

Myo5b Transports Fibronectin-Containing Vesicles and Facilitates FN1 Secretion from Human Pleural Mesothelial Cells

Pleural mesothelial cells (PMCs) play a central role in the progression of pleural fibrosis. As pleural injury progresses to fibrosis, PMCs transition to mesenchymal myofibroblast via mesothelial mesenchymal transition (MesoMT), and produce extracellular matrix (ECM) proteins including collagen and...

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Bibliographic Details
Main Authors: Tsuyoshi Sakai, Young-yeon Choo, Osamu Sato, Reiko Ikebe, Ann Jeffers, Steven Idell, Torry Tucker, Mitsuo Ikebe
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
fibronectin
myosin 5b
fibrosis
mesothelial cell
vesicle transport
secretion
Online Access:https://www.mdpi.com/1422-0067/23/9/4823

Internet

https://www.mdpi.com/1422-0067/23/9/4823

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