Detection of CCR5Δ32 Mutant Alleles in Heterogeneous Cell Mixtures Using Droplet Digital PCR

The C-C chemokine receptor type 5 (CCR5 or CD195) is one of the co-receptor binding sites of the human immunodeficiency virus (HIV). Transplantations of hematopoietic stem cells with the CCR5Δ32 knockout mutation could represent an effective tool for the complete cure of HIV; these methods having pa...

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Bibliographic Details
Main Authors: Alyona Sorokina, Alexander Artyuhov, Alexandra Goltsova, Erdem Dashinimaev
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.805931/full