Determination of PAR4 numbers on the surface of human platelets: no effect of the single nucleotide polymorphism rs773902

The thrombin receptor, protease-activated receptor 4 (PAR4), is important for platelet activation and is the target of emerging anti-thrombotic drugs. A frequently occurring single nucleotide polymorphism (SNP; rs773902) causes a function-altering PAR4 sequence variant (NC_000019.10:p.Ala120Thr), wh...

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Bibliographic Details
Main Authors: Simeng Li, Volga Tarlac, Roberto B. I. Christanto, Shauna L. French, Justin R. Hamilton
Format: Article
Language:English
Published: Taylor & Francis Group 2021-10-01
Series:Platelets
Subjects:
Online Access:http://dx.doi.org/10.1080/09537104.2020.1810654