Single cell analysis reveals immune cell–adipocyte crosstalk regulating the transcription of thermogenic adipocytes

Single cell analysis reveals immune cell–adipocyte crosstalk regulating the transcription of thermogenic adipocytes

Immune cells are vital constituents of the adipose microenvironment that influence both local and systemic lipid metabolism. Mice lacking IL10 have enhanced thermogenesis, but the roles of specific cell types in the metabolic response to IL10 remain to be defined. We demonstrate here that selective...

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Bibliographic Details
Main Authors: Prashant Rajbhandari, Douglas Arneson, Sydney K Hart, In Sook Ahn, Graciel Diamante, Luis C Santos, Nima Zaghari, An-Chieh Feng, Brandon J Thomas, Laurent Vergnes, Stephen D Lee, Abha K Rajbhandari, Karen Reue, Stephen T Smale, Xia Yang, Peter Tontonoz
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-10-01
Series:eLife
Subjects:
adipocyte
metabolism
cytokine
Online Access:https://elifesciences.org/articles/49501

Internet

https://elifesciences.org/articles/49501

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