Therapeutic vaccination following early antiretroviral therapy elicits highly functional T cell responses against conserved HIV-1 regions

Therapeutic vaccination following early antiretroviral therapy elicits highly functional T cell responses against conserved HIV-1 regions

Abstract ‘Kick and kill’ cure strategies aim to induce HIV protein expression in latently infected cells (kick), and thus trigger their elimination by cytolytic T cells (kill). In the Research in Viral Eradication of HIV Reservoirs trial (NCT02336074), people diagnosed with primary HIV infection rec...

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Bibliographic Details
Main Authors: Jakub Kopycinski, Hongbing Yang, Gemma Hancock, Matthew Pace, Ellen Kim, John Frater, Wolfgang Stöhr, Tomás Hanke, Sarah Fidler, Lucy Dorrell, RIVER trial study group
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-42888-3

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https://doi.org/10.1038/s41598-023-42888-3

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