The way to precision medicine in gynecologic cancers: The first case report of an exceptional response to alpelisib in a PIK3CA-mutated endometrial cancer

The way to precision medicine in gynecologic cancers: The first case report of an exceptional response to alpelisib in a PIK3CA-mutated endometrial cancer

Endometrial cancer (EC) is the most common gynecologic cancer in Europe and its prevalence is increasing. EC includes a biological and clinical heterogeneous group of tumors, usually classified as type I (endometrioid) or type II (non-endometrioid) based on the histopathological characteristics. In...

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Bibliographic Details
Main Authors: Anna Passarelli, Jole Ventriglia, Carmela Pisano, Sabrina Chiara Cecere, Marilena Di Napoli, Sabrina Rossetti, Rosa Tambaro, Luca Tarotto, Francesco Fiore, Alberto Farolfi, Michele Bartoletti, Sandro Pignata
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Oncology
Subjects:
alpelisib
endometrial cancer
phosphatidylinositol 3-kinase (PI3K) pathway
genomic profiling
PI3K inhibitor
PIK3CA mutation
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1088962/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.1088962/full

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