Genetic heterogeneity of the β-globin gene in various geographic populations of Yunnan in southwestern China.

The aim of this study was to investigate the geographic distribution of β-globin gene mutations in different ethnic groups in Yunnan province.From 2004 to 2014, 1,441 subjects with hemoglobin disorders, identified by PCR-reverse dot blot and DNA sequencing, were studied according to ethnicity and ge...

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Bibliographic Details
Main Authors: Jie Zhang, Jing He, Xiao-Hong Zeng, Shi-Jun Ge, Yu Huang, Jie Su, Xue-Mei Ding, Ji-Qing Yang, Yong-Jiu Cao, Hong Chen, Ying-Hong Zhang, Bao-Sheng Zhu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4388507?pdf=render