Characterization of mechanisms positioning costimulatory complexes in immune synapses

Characterization of mechanisms positioning costimulatory complexes in immune synapses

Summary: Small immunoglobulin superfamily (sIGSF) adhesion complexes form a corolla of microdomains around an integrin ring and secretory core during immunological synapse (IS) formation. The corolla recruits and retains major costimulatory/checkpoint complexes, such as CD28, making forces that gove...

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Bibliographic Details
Main Authors: Anastasios Siokis, Philippe A. Robert, Philippos Demetriou, Audun Kvalvaag, Salvatore Valvo, Viveka Mayya, Michael L. Dustin, Michael Meyer-Hermann
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:iScience
Subjects:
Cell biology
Computational bioinformatics
Computational molecular modelling
Immunology
Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221010683

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http://www.sciencedirect.com/science/article/pii/S2589004221010683

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