Identification of cellular heterogeneity and immunogenicity of chondrocytes via single-cell RNA sequencing technique in human osteoarthritis

Identification of cellular heterogeneity and immunogenicity of chondrocytes via single-cell RNA sequencing technique in human osteoarthritis

Background: Osteoarthritis (OA) has placed a heavy burden to the economy and humanistics. To explore the biological functions and markers of chondrocytes contributes significantly to the accurate diagnosis and targeted treatment of OA.Methods: We systematically analyzed the immunogenicity and biolog...

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Bibliographic Details
Main Authors: Xinyue Hu, Zhuang Li, Mingliang Ji, Yucheng Lin, Yuzhi Chen, Jun Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Pharmacology
Subjects:
single-cell RNA sequencing (scRNA-seq)
osteoarthritis
heterogeneity
immunogenicity
bulk RNA sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1004766/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.1004766/full

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