Lipocalin-2 induces mitochondrial dysfunction in renal tubular cells via mTOR pathway activation
Summary: Mitochondrial dysfunction is a critical process in renal epithelial cells upon kidney injury. While its implication in kidney disease progression is established, the mechanisms modulating it remain unclear. Here, we describe the role of Lipocalin-2 (LCN2), a protein expressed in injured tub...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-09-01
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Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124723010434 |