Non-linear leak currents affect mammalian neuron physiology

Non-linear leak currents affect mammalian neuron physiology

In their seminal works on squid giant axons, Hodgkin and Huxley approximated the membrane leak current as Ohmic, i.e. linear, since in their preparation, sub-threshold current rectification due to the influence of ionic concentration is negligible. Most studies on mammalian neurons have made the sam...

Full description

Bibliographic Details
Main Authors: Shiwei eHuang, Sungho eHong, Erik eDe Schutter
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Passive membrane properties
ionic concentration-dependence
Goldman-Hodgkin-Katz equation
time constant and input resistance
cerebellar Purkinje neurons.
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00432/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00432/full

Similar Items