Anti-Melanogenesis Effect of <i>Rosa rugosa</i> on α-MSH-Induced B16F10 Cells via PKA/CREB Pathway Activation

Anti-Melanogenesis Effect of <i>Rosa rugosa</i> on α-MSH-Induced B16F10 Cells via PKA/CREB Pathway Activation

Melanin protects the skin against UV damage, whereas excessive melanin accumulation causes abnormal pigmentation and even melanoma. It has been reported that <i>Rosa rugosa</i> exhibits antioxidant, anti-bacterial, anti-tumor, and anti-inflammation activities. The current study evaluated...

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Bibliographic Details
Main Authors: Xianrong Zhou, Jung Hwan Oh, Fatih Karadeniz, Jiho Yang, Hyunjung Lee, Youngwan Seo, Chang-Suk Kong
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Applied Sciences
Subjects:
B16F10 melanoma cells
melanogenesis
PKA/CREB signaling pathway
<i>Rosa rugosa</i>
α-MSH
Online Access:https://www.mdpi.com/2076-3417/13/1/184

Internet

https://www.mdpi.com/2076-3417/13/1/184

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