Experimental validation of immunogenic SARS-CoV-2 T cell epitopes identified by artificial intelligence

Experimental validation of immunogenic SARS-CoV-2 T cell epitopes identified by artificial intelligence

During the COVID-19 pandemic we utilized an AI-driven T cell epitope prediction tool, the NEC Immune Profiler (NIP) to scrutinize and predict regions of T cell immunogenicity (hotspots) from the entire SARS-CoV-2 viral proteome. These immunogenic regions offer potential for the development of univer...

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Bibliographic Details
Main Authors: Lorenzo Federico, Brandon Malone, Simen Tennøe, Viktoriia Chaban, Julie Røkke Osen, Murat Gainullin, Eva Smorodina, Hassen Kared, Rahmad Akbar, Victor Greiff, Richard Stratford, Trevor Clancy, Ludvig Andre Munthe
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
T cell
COVID-19
CD8+ lymphocytes
CD4+ lymphocytes
vaccine
SARS-CoV-2
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1265044/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1265044/full

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