Increases in myocardial workload induced by rapid atrial pacing trigger alterations in global metabolism.

To determine whether increases in cardiac work lead to alterations in the plasma metabolome and whether such changes arise from the heart or peripheral organs.There is growing evidence that the heart influences systemic metabolism through endocrine effects and affecting pathways involved in energy h...

Full description

Bibliographic Details
Main Authors: Aslan T Turer, Gregory D Lewis, John F O'Sullivan, Sammy Elmariah, Jessica L Mega, Tayo A Addo, Marc S Sabatine, James A de Lemos, Robert E Gerszten
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4059652?pdf=render