Low pre-transplant levels of mannose-binding lectin are associated with viral infections and mortality after haematopoietic allogeneic stem cell transplantation

Low pre-transplant levels of mannose-binding lectin are associated with viral infections and mortality after haematopoietic allogeneic stem cell transplantation

Abstract Background Mannose-binding lectin (MBL) is a key component of innate immunity. Low serum MBL levels, related to promoter polymorphism and structural variants, have been associated with an increased risk of infection. The aim of this work was to analyse the incidence and severity of infectio...

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Bibliographic Details
Main Authors: M. Puente, C. Fariñas-Alvarez, A. Moreto, P. Sánchez-Velasco, J. G. Ocejo-Vinyals, M. C. Fariñas, on behalf of SCT team
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Immunology
Subjects:
Allo-HSCT
Genetic polymorphism
MBL
Infection
Outcome
Online Access:http://link.springer.com/article/10.1186/s12865-019-0318-8

Internet

http://link.springer.com/article/10.1186/s12865-019-0318-8

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