A Modular Differentiation System Maps Multiple Human Kidney Lineages from Pluripotent Stem Cells

Summary: Recent studies using human pluripotent stem cells (hPSCs) have developed protocols to induce kidney-lineage cells and reconstruct kidney organoids. However, the separate generation of metanephric nephron progenitors (NPs), mesonephric NPs, and ureteric bud (UB) cells, which constitute embry...

Full description

Bibliographic Details
Main Authors: Hiraku Tsujimoto, Tomoko Kasahara, Shin-ichi Sueta, Toshikazu Araoka, Satoko Sakamoto, Chihiro Okada, Shin-ichi Mae, Taiki Nakajima, Natsumi Okamoto, Daisuke Taura, Makoto Nasu, Tatsuya Shimizu, Makoto Ryosaka, Zhongwei Li, Masakatsu Sone, Makoto Ikeya, Akira Watanabe, Kenji Osafune
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720303545