Recovery of reduced thiol groups by superoxide-mediated denitrosation of nitrosothiols

Nitrosation of critical thiols has been elaborated as reversible posttranslational modification with regulatory function in multiple disorders. Reversibility of S-nitrosation is generally associated with enzyme-mediated one-electron reductions, catalyzed by the thioredoxin system, or by nitrosogluta...

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Bibliographic Details
Main Authors: Stefan Schildknecht, Alex von Kriegsheim, Ksenija Vujacic-Mirski, Fabio Di Lisa, Volker Ullrich, Andreas Daiber
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722002117