Gender Difference in Lithium-Induced Sodium Current Dysregulation and Ventricular Arrhythmogenesis in Right Ventricular Outflow Tract Cardiomyocytes

Lithium intoxication induces Brugada-pattern ECG, ventricular arrhythmia, and sudden death with the predominant preference for the male over the female gender. This study investigated the mechanisms of gender difference in lithium-induced arrhythmogenesis. The ECG parameters were recorded in male an...

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Autors principals: Ching-Han Liu, Yao-Chang Chen, Yen-Yu Lu, Yung-Kuo Lin, Satoshi Higa, Shih-Ann Chen, Yi-Jen Chen
Format: Article
Idioma:English
Publicat: MDPI AG 2022-10-01
Col·lecció:Biomedicines
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Accés en línia:https://www.mdpi.com/2227-9059/10/11/2727