Gender Difference in Lithium-Induced Sodium Current Dysregulation and Ventricular Arrhythmogenesis in Right Ventricular Outflow Tract Cardiomyocytes

Gender Difference in Lithium-Induced Sodium Current Dysregulation and Ventricular Arrhythmogenesis in Right Ventricular Outflow Tract Cardiomyocytes

Lithium intoxication induces Brugada-pattern ECG, ventricular arrhythmia, and sudden death with the predominant preference for the male over the female gender. This study investigated the mechanisms of gender difference in lithium-induced arrhythmogenesis. The ECG parameters were recorded in male an...

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Bibliographic Details
Main Authors: Ching-Han Liu, Yao-Chang Chen, Yen-Yu Lu, Yung-Kuo Lin, Satoshi Higa, Shih-Ann Chen, Yi-Jen Chen
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Biomedicines
Subjects:
Brugada syndrome
gender
lithium intoxication
sodium current dysregulation
right ventricular outflow tract
Online Access:https://www.mdpi.com/2227-9059/10/11/2727

Internet

https://www.mdpi.com/2227-9059/10/11/2727

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