Andrographolide induces protective autophagy and targeting DJ-1 triggers reactive oxygen species-induced cell death in pancreatic cancer

Andrographolide induces protective autophagy and targeting DJ-1 triggers reactive oxygen species-induced cell death in pancreatic cancer

Background Andrographolide (Andro), an extract of Andrographis paniculate (Burm.f.) Wall. ex Nees (Acanthaceae), possesses diverse biologically active properties. However, the precise mechanisms and effects of Andro on pancreatic cancer (PC) remain unclear. Methods The cytotoxic potential of Andro a...

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Bibliographic Details
Main Authors: Zhaohong Wang, Hui Chen, Xufan Cai, Heqi Bu, Shengzhang Lin
Format: Article
Language:English
Published: PeerJ Inc. 2024-06-01
Series:PeerJ
Subjects:
Andrographolide
DJ-1
Reactive oxygen species
Protective autophagy
Pancreatic cancer
Online Access:https://peerj.com/articles/17619.pdf

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https://peerj.com/articles/17619.pdf

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