High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance

High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance

High-fat diet plays a role in development of insulin resistance. Here, the authors report a mechanism that underlies the development of diet induced insulin resistance through the activation of an aryl hydrocarbon receptor mediated signalling pathway in the liver by faecal exosomes derived from inte...

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Bibliographic Details
Main Authors: Anil Kumar, Kumaran Sundaram, Jingyao Mu, Gerald W. Dryden, Mukesh K. Sriwastva, Chao Lei, Lifeng Zhang, Xiaolan Qiu, Fangyi Xu, Jun Yan, Xiang Zhang, Juw Won Park, Michael L. Merchant, Henry C. L. Bohler, Baomei Wang, Shuangqin Zhang, Chao Qin, Ziying Xu, Xianlin Han, Craig J. McClain, Yun Teng, Huang-Ge Zhang
Format: Article
Language:English
Published: Nature Portfolio 2021-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20500-w

Internet

https://doi.org/10.1038/s41467-020-20500-w

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