The role of α-sheet structure in amyloidogenesis: characterization and implications
Amyloid diseases are linked to protein misfolding whereby the amyloidogenic protein undergoes a conformational change, aggregates and eventually forms amyloid fibrils. While the amyloid fibrils and plaques are hallmarks of these diseases, they typically form late in the disease process and do not co...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
The Royal Society
2022-11-01
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Series: | Open Biology |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/10.1098/rsob.220261 |