PCR-based techniques for leprosy diagnosis: from the laboratory to the clinic.

In leprosy, classic diagnostic tools based on bacillary counts and histopathology have been facing hurdles, especially in distinguishing latent infection from active disease and diagnosing paucibacillary clinical forms. Serological tests and IFN-gamma releasing assays (IGRA) that employ humoral and...

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Bibliographic Details
Main Authors: Alejandra Nóbrega Martinez, Carolina Talhari, Milton Ozório Moraes, Sinésio Talhari
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-04-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3983108?pdf=render