Production of two SARS-CoV-2 neutralizing antibodies with different potencies in Nicotiana benthamiana

Production of two SARS-CoV-2 neutralizing antibodies with different potencies in Nicotiana benthamiana

Monoclonal antibodies are considered to be highly effective therapeutic tools for the treatment of mild to moderate COVID-19 patients. In the present work, we describe the production of two SARS-CoV-2 human IgG1 monoclonal antibodies recognizing the spike protein receptor-binding domain (RBD) and en...

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Bibliographic Details
Main Authors: Rachele Frigerio, Carla Marusic, Maria Elena Villani, Chiara Lico, Cristina Capodicasa, Emanuele Andreano, Ida Paciello, Rino Rappuoli, Anna Maria Salzano, Andrea Scaloni, Selene Baschieri, Marcello Donini
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Plant Science
Subjects:
molecular farming
COVID-19
transient expression
proteolytic degradation
monoclonal antibodies (mAbs)
Online Access:https://www.frontiersin.org/articles/10.3389/fpls.2022.956741/full

Internet

https://www.frontiersin.org/articles/10.3389/fpls.2022.956741/full

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