Phase 1 Study to Evaluate the Safety of Reducing the Prophylactic Dose of Dexamethasone around Docetaxel Infusion in Patients with Prostate and Breast Cancer

Phase 1 Study to Evaluate the Safety of Reducing the Prophylactic Dose of Dexamethasone around Docetaxel Infusion in Patients with Prostate and Breast Cancer

Background: There is little evidence that supports the registered high dose of dexamethasone used around docetaxel. However, this high dose is associated with considerable side effects. This study evaluates the feasibility of reducing the prophylactic oral dosage of dexamethasone around docetaxel in...

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Bibliographic Details
Main Authors: Rieneke T. Lugtenberg, Stefanie de Groot, Danny Houtsma, Vincent O. Dezentjé, Annelie J. E. Vulink, Maarten J. Fischer, Johanneke E. A. Portielje, Jacobus J. M. van der Hoeven, Hans Gelderblom, Hanno Pijl, Judith R. Kroep
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cancers
Subjects:
prostate cancer
breast cancer
dexamethasone
docetaxel
toxicity
hypersensitivity reactions
Online Access:https://www.mdpi.com/2072-6694/15/6/1691

Internet

https://www.mdpi.com/2072-6694/15/6/1691

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