First Succinylome Profiling of Vibrio alginolyticus Reveals Key Role of Lysine Succinylation in Cellular Metabolism and Virulence

First Succinylome Profiling of Vibrio alginolyticus Reveals Key Role of Lysine Succinylation in Cellular Metabolism and Virulence

Recent studies have shown that a key strategy of many pathogens is to use post-translational modification (PTMs) to modulate host factors critical for infection. Lysine succinylation (Ksuc) is a major PTM widespread in prokaryotic and eukaryotic cells, and is associated with the regulation of numero...

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Bibliographic Details
Main Authors: Fuyuan Zeng, Huanying Pang, Ying Chen, Hongwei Zheng, Wanxin Li, Srinivasan Ramanathan, Rowena Hoare, Sean J. Monaghan, Xiangmin Lin, Jichang Jian
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Vibrio alginolyticus
lysine succinylation
acetylation
crosstalk
virulence factors
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2020.626574/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2020.626574/full

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