Aging Additively Influences Insulin- and Insulin-Like Growth Factor-1-Mediated Endothelial Dysfunction and Antioxidant Deficiency in Spontaneously Hypertensive Rats

Aging Additively Influences Insulin- and Insulin-Like Growth Factor-1-Mediated Endothelial Dysfunction and Antioxidant Deficiency in Spontaneously Hypertensive Rats

This study aimed to investigate the aging-related endothelial dysfunction mediated by insulin and insulin-like growth factor-1 (IGF-1) and antioxidant deficiency in hypertension. Male spontaneously hypertensive rats (SHRs) and age-matched normotensive Wistar–Kyoto rats (WKYs) were randomly divided i...

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Bibliographic Details
Main Authors: Kunanya Masodsai, Yi-Yuan Lin, Sih-Yin Lin, Chia-Ting Su, Shin-Da Lee, Ai-Lun Yang
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Biomedicines
Subjects:
aging
hypertension
endothelium
antioxidant activity
oxidative stress
Online Access:https://www.mdpi.com/2227-9059/9/6/676

Internet

https://www.mdpi.com/2227-9059/9/6/676

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