Chronic Arsenic Exposure Upregulates the Expression of Basal Transcriptional Factors and Increases Invasiveness of the Non-Muscle Invasive Papillary Bladder Cancer Line RT4

Chronic Arsenic Exposure Upregulates the Expression of Basal Transcriptional Factors and Increases Invasiveness of the Non-Muscle Invasive Papillary Bladder Cancer Line RT4

The bladder is a target organ for inorganic arsenic, a carcinogen and common environmental contaminant found in soil and water. Urothelial carcinoma (UC) is the most common type of bladder cancer (BC) that develops into papillary or non-papillary tumors. Papillary tumors are mostly non-muscle invasi...

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Bibliographic Details
Main Authors: Aaron A. Mehus, Nicholas Bergum, Peter Knutson, Swojani Shrestha, Matthew Kalonick, Xudong Zhou, Scott H. Garrett, Donald A. Sens, Mary Ann Sens, Seema Somji
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
arsenite
heavy metal
urothelial carcinoma
luminal
basal
Online Access:https://www.mdpi.com/1422-0067/23/20/12313

Internet

https://www.mdpi.com/1422-0067/23/20/12313

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