The effect of red betel (Piper crocatum) water fraction as tyrosinase inhibitors: In vitro, molecular docking, and molecular dynamics studies

The effect of red betel (Piper crocatum) water fraction as tyrosinase inhibitors: In vitro, molecular docking, and molecular dynamics studies

Objective: Excessive melanin expression can lead to dermatological conditions such as Riehl melanosis, lentigo, freckles, and melasma post-inflammatory hyperpigmentation. Targeting melanogenesis, the synthesis of melanin, and inhibiting tyrosinase have been explored to mitigate its effects. However,...

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Bibliographic Details
Main Authors: Mega Safithri, Dimas Andrianto, Adzani Gaisani Arda, Putri Hawa Syaifie, Nofa Mardia Ningsih Kaswati, Etik Mardliyati, Donny Ramadhan, Muhammad Miftah Jauhar, Dwi Wahyu Nugroho, Dewi Anggraini Septaningsih, Leni Tria Melati, Martini Hudayanti, Eliwati Sarah, Riyan Alifibi Putera Irsal, Nurul Taufiqu Rochman
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Journal of King Saud University: Science
Subjects:
In silico
In vitro
Pigmentation
Molecular docking
Molecular dynamics
Red betel
Online Access:http://www.sciencedirect.com/science/article/pii/S1018364723003956

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http://www.sciencedirect.com/science/article/pii/S1018364723003956

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