Anticancer Potential of Pyridoxine-Based Doxorubicin Derivatives: An In Vitro Study

Anticancer Potential of Pyridoxine-Based Doxorubicin Derivatives: An In Vitro Study

Doxorubicin (DOX) is a prevalent anticancer agent; however, it is unfortunately characterized by high cardiotoxicity, myelosuppression, and multiple other side effects. To overcome DOX limitations, two novel pyridoxine-derived doxorubicin derivatives were synthesized (DOX-1 and DOX-2). In the presen...

Full description

Bibliographic Details
Main Authors: Rawdah Karwt, Oksana V. Bondar, Mikhail V. Pugachev, Tharaa Mohammad, Aisylu S. Kadyrova, Roman S. Pavelyev, Saleh Alrhmoun, Oleg I. Gnezdilov, Yurii G. Shtyrlin
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Life
Subjects:
doxorubicin
anticancer agents
doxorubicin derivatives
pyridoxine
vitamin B6
apoptosis induction
Online Access:https://www.mdpi.com/2075-1729/14/3/282

Internet

https://www.mdpi.com/2075-1729/14/3/282

Similar Items