MiR-375 and miR-5691 exert anti-fibroproliferative effects on hypertrophic scar fibroblasts by suppressing thrombospondin 1 expression

MiR-375 and miR-5691 exert anti-fibroproliferative effects on hypertrophic scar fibroblasts by suppressing thrombospondin 1 expression

Background: Hypertrophic scar (HS) is characterized by the hyperproliferation of fibroblasts and the excessive deposition of extracellular matrix (ECM). Thrombospondin 1 (THBS1) is a component of the ECM, which has been implicated in HS formation. Objectives: This study aimed to explore whether miR-...

Full description

Bibliographic Details
Main Authors: Xiaoliang Zhou, Hua Ye, Xianlin Wang, Jiajin Tu, Jing Lv
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Dermatologica Sinica
Subjects:
fibroblasts
hypertrophic scar
mir-375
mir-5691
thrombospondin 1
Online Access:http://www.dermsinica.org/article.asp?issn=1027-8117;year=2022;volume=40;issue=1;spage=34;epage=43;aulast=Zhou

Internet

http://www.dermsinica.org/article.asp?issn=1027-8117;year=2022;volume=40;issue=1;spage=34;epage=43;aulast=Zhou

Similar Items