Optogenetic manipulation and photoacoustic imaging using a near-infrared transgenic mouse model

Optogenetic manipulation and photoacoustic imaging using a near-infrared transgenic mouse model

Optogenetic tools can be used as in vivo imaging probes. Here the authors generate a loxP-BphP1 transgenic mouse to enable Cre-dependent temporal and spatial targeting of BphP1 expression in vivo; they show photoacoustic tomography of BphP1 expression in developing embryos and regenerating livers.

Bibliographic Details
Main Authors: Ludmila A. Kasatkina, Chenshuo Ma, Mikhail E. Matlashov, Tri Vu, Mucong Li, Andrii A. Kaberniuk, Junjie Yao, Vladislav V. Verkhusha
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-30547-6

Internet

https://doi.org/10.1038/s41467-022-30547-6

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