Optogenetic manipulation and photoacoustic imaging using a near-infrared transgenic mouse model
Optogenetic tools can be used as in vivo imaging probes. Here the authors generate a loxP-BphP1 transgenic mouse to enable Cre-dependent temporal and spatial targeting of BphP1 expression in vivo; they show photoacoustic tomography of BphP1 expression in developing embryos and regenerating livers.
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-05-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-30547-6 |
| _version_ | 1811338849328037888 |
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| author | Ludmila A. Kasatkina Chenshuo Ma Mikhail E. Matlashov Tri Vu Mucong Li Andrii A. Kaberniuk Junjie Yao Vladislav V. Verkhusha |
| author_facet | Ludmila A. Kasatkina Chenshuo Ma Mikhail E. Matlashov Tri Vu Mucong Li Andrii A. Kaberniuk Junjie Yao Vladislav V. Verkhusha |
| author_sort | Ludmila A. Kasatkina |
| collection | DOAJ |
| description | Optogenetic tools can be used as in vivo imaging probes. Here the authors generate a loxP-BphP1 transgenic mouse to enable Cre-dependent temporal and spatial targeting of BphP1 expression in vivo; they show photoacoustic tomography of BphP1 expression in developing embryos and regenerating livers. |
| first_indexed | 2024-04-13T18:16:41Z |
| format | Article |
| id | doaj.art-19a3d9b1e76a4652a521331cc3207f17 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-13T18:16:41Z |
| publishDate | 2022-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-19a3d9b1e76a4652a521331cc3207f172022-12-22T02:35:38ZengNature PortfolioNature Communications2041-17232022-05-0113111610.1038/s41467-022-30547-6Optogenetic manipulation and photoacoustic imaging using a near-infrared transgenic mouse modelLudmila A. Kasatkina0Chenshuo Ma1Mikhail E. Matlashov2Tri Vu3Mucong Li4Andrii A. Kaberniuk5Junjie Yao6Vladislav V. Verkhusha7Department of Genetics and Gruss-Lipper Biophotonics Center, Albert Einstein College of MedicineDepartment of Biomedical Engineering, Duke UniversityDepartment of Genetics and Gruss-Lipper Biophotonics Center, Albert Einstein College of MedicineDepartment of Biomedical Engineering, Duke UniversityDepartment of Biomedical Engineering, Duke UniversityDepartment of Genetics and Gruss-Lipper Biophotonics Center, Albert Einstein College of MedicineDepartment of Biomedical Engineering, Duke UniversityDepartment of Genetics and Gruss-Lipper Biophotonics Center, Albert Einstein College of MedicineOptogenetic tools can be used as in vivo imaging probes. Here the authors generate a loxP-BphP1 transgenic mouse to enable Cre-dependent temporal and spatial targeting of BphP1 expression in vivo; they show photoacoustic tomography of BphP1 expression in developing embryos and regenerating livers.https://doi.org/10.1038/s41467-022-30547-6 |
| spellingShingle | Ludmila A. Kasatkina Chenshuo Ma Mikhail E. Matlashov Tri Vu Mucong Li Andrii A. Kaberniuk Junjie Yao Vladislav V. Verkhusha Optogenetic manipulation and photoacoustic imaging using a near-infrared transgenic mouse model Nature Communications |
| title | Optogenetic manipulation and photoacoustic imaging using a near-infrared transgenic mouse model |
| title_full | Optogenetic manipulation and photoacoustic imaging using a near-infrared transgenic mouse model |
| title_fullStr | Optogenetic manipulation and photoacoustic imaging using a near-infrared transgenic mouse model |
| title_full_unstemmed | Optogenetic manipulation and photoacoustic imaging using a near-infrared transgenic mouse model |
| title_short | Optogenetic manipulation and photoacoustic imaging using a near-infrared transgenic mouse model |
| title_sort | optogenetic manipulation and photoacoustic imaging using a near infrared transgenic mouse model |
| url | https://doi.org/10.1038/s41467-022-30547-6 |
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