Multidrug chemotherapy, whole-brain radiation and cytarabine therapy for primary central nervous system lymphoma in elderly patients with dose modification based on geriatric assessment: study protocol for a phase II, multicentre, non-randomised study

Multidrug chemotherapy, whole-brain radiation and cytarabine therapy for primary central nervous system lymphoma in elderly patients with dose modification based on geriatric assessment: study protocol for a phase II, multicentre, non-randomised study

Introduction Multidrug chemoimmunotherapy with rituximab, high-dose methotrexate, procarbazine and vincristine (R-MPV) is a standard therapy for younger patients with primary central nervous system lymphoma (PCNSL); however, prospective data regarding its use in elderly patients are lacking. This mu...

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Bibliographic Details
Main Authors: Kenji Yoshida, Tomoyuki Akita, Kosuke Katayama, Kiyohide Kakuta, Takafumi Nishizaki, Fumiyuki Yamasaki, Hirotaka Fudaba, Kenichiro Asano, Takashi Sasayama, Manabu Natsumeda, Taichi Shimabukuro, Kotaro Taguchi, Shinichiro Koizumi, Noriyuki Nakayama, Kentaro Fujii, Ikuno Nishibuchi, Kazuhiko Sugiyama, Ushio Yonezawa, Momii Yasutomo, Yukari Kawasaki, Kazuhiro Tanaka, Hiroaki Nagashima, Yoshihiro Tsukamoto, Makoto Ideguchi, Kazuhiko Kurozumi, Tomohiro Hosoya, Atsushi Kambe
Format: Article
Language:English
Published: BMJ Publishing Group 2023-04-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/13/4/e071350.full

Internet

https://bmjopen.bmj.com/content/13/4/e071350.full

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