Structure sampling for computational estimation of localized DNA interaction rates

Abstract Molecular circuits implemented using molecular components tethered to a DNA tile nanostructure have certain advantages over solution-phase circuits. Tethering components in close proximity increases the speed of reactions by reducing diffusion and improves scalability by enabling reuse of i...

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Bibliographic Details
Main Authors: Sarika Kumar, Julian M. Weisburd, Matthew R. Lakin
Format: Article
Language:English
Published: Nature Portfolio 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92145-8