The study of the impact of additional chromosomal aberrations and c-MYC and BCR::ABL1 genes amplification on CML patient’s characteristics: relation to haematological parameters and patient outcome

The study of the impact of additional chromosomal aberrations and c-MYC and BCR::ABL1 genes amplification on CML patient’s characteristics: relation to haematological parameters and patient outcome

Abstract Background Chronic myeloid leukaemia is characterised by genetic instability which results in additional cytogenetic aberrations that have been linked to progression to advanced phase. Genomic study linked amplified genes in the form of c-MYC and/or the rare BCR::ABL1 genes amplification to...

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Bibliographic Details
Main Authors: Hend Attia, Dina Adel Fouad, Heba Samy
Format: Article
Language:English
Published: SpringerOpen 2023-12-01
Series:Egyptian Journal of Medical Human Genetics
Subjects:
CML
ACA
BCR::ABL1
c-MYC
Gene amplification
Online Access:https://doi.org/10.1186/s43042-023-00460-8

Internet

https://doi.org/10.1186/s43042-023-00460-8

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