Flavivirus prM interacts with MDA5 and MAVS to inhibit RLR antiviral signaling

Flavivirus prM interacts with MDA5 and MAVS to inhibit RLR antiviral signaling

Abstract Background Vector-borne flaviviruses, including tick-borne encephalitis virus (TBEV), Zika virus (ZIKV), West Nile virus (WNV), yellow fever virus (YFV), dengue virus (DENV), and Japanese encephalitis virus (JEV), pose a growing threat to public health worldwide, and have evolved complex me...

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Bibliographic Details
Main Authors: Liyan Sui, Yinghua Zhao, Wenfang Wang, Hongmiao Chi, Tian Tian, Ping Wu, Jinlong Zhang, Yicheng Zhao, Zheng-Kai Wei, Zhijun Hou, Guoqiang Zhou, Guoqing Wang, Zedong Wang, Quan Liu
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Cell & Bioscience
Subjects:
Flavivirus
Precursor membrane protein
MDA5
MAVS
RLR signaling
Online Access:https://doi.org/10.1186/s13578-023-00957-0

Internet

https://doi.org/10.1186/s13578-023-00957-0

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