Oxidized Forms of Ergothioneine Are Substrates for Mammalian Thioredoxin Reductase

Ergothioneine (EGT) is a sulfur-containing amino acid analog that is biosynthesized in fungi and bacteria, accumulated in plants, and ingested by humans where it is concentrated in tissues under oxidative stress. While the physiological function of EGT is not yet fully understood, EGT is a potent an...

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Bibliographic Details
Main Authors: Kaelyn A. Jenny, Gracyn Mose, Daniel J. Haupt, Robert J. Hondal
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/11/2/185