Mesothelioma tumor cells modulate dendritic cell lipid content, phenotype and function.

Dendritic cells (DCs) play an important role in the generation of anti-cancer immune responses, however there is evidence that DCs in cancer patients are dysfunctional. Lipid accumulation driven by tumor-derived factors has recently been shown to contribute to DC dysfunction in several human cancers...

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Bibliographic Details
Main Authors: Joanne K Gardner, Cyril D S Mamotte, Priya Patel, Teong Ling Yeoh, Connie Jackaman, Delia J Nelson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4401725?pdf=render