Fatty acid binding protein 4/aP2-dependent BLT1R expression and signaling

Fatty acid binding protein 4/aP2-dependent BLT1R expression and signaling

Previous studies have shown that reduced levels of the adipocyte fatty acid binding protein (FABP)4 (AFABP/aP2), result in metabolic improvement including potentiated insulin sensitivity and attenuated atherosclerosis. Mechanistically, pharmacologic or genetic inhibition of FABP4 in macrophages upre...

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Bibliographic Details
Main Authors: Ann V. Hertzel, Hongliang Xu, Michael Downey, Nicholas Kvalheim, David A. Bernlohr
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Journal of Lipid Research
Subjects:
macrophages
leukotrienes
inflammation
lipids
lipid mediators
signal transduction
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520335860

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520335860

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